Preoperative CD52 Level Predicts Graft Survival following Kidney Transplantation

Table 2

Univariate and multivariate analyses of preoperative and postoperative factors affecting graft loss.

Variables	Comparison	(%)	Univariate		Multivariate
			HR (95% CI)	value	HR (95% CI)	value
Age	≥50	56 (58%)	1.406 (0.582–3.395)	0.449
	<50	40 (42%)
Gender	Male	62 (64.5%)	0.849 (0.346–2.085)	0.721
	Female	34 (35.5%)
Serum creatinine (6 months after KTx)	0.7–6		1.908 (1.192–3.053)	0.007	1.700 (1.022–2.828)	0.041
Acute allograft rejection	Yes	17 (17.7%)	2.997 (1.239–7.250)	0.015	2.919 (1.118–7.623)	0.029
	No	79 (82.3%)
DGF	Yes	20 (20.8%)	2.672 (1.113–6.412)	0.028	1.361 (0.500–3.706)	0.546
	No	76 (79.2%)
Total HLA mismatch	≤2	34 (35.4%)	1.169 (0.868–1.576)	0.304
	>2	62 (64.6%)
BK virus infection	Yes	17 (17.7%)	2.673 (0.856–8.348)	0.091	0.988; (0.224–4.366)	0.987
	No	79 (82.3%)
Serum levels of CD52	CD52 ≥260 pg/mL	39 (40.6%)	3.168 (1.346–7.454)	0.008	3.114 (1.026–9.604)	0.045
	CD52 <260 pg/mL	57 (59.4%)

DGF: delayed graft function; HLA: human leukocyte antigen; KTx: kidney transplantation.