Review Article

A Review of the Antimicrobial Potential of Musca domestica as a Natural Approach with Promising Prospects to Countermeasure Antibiotic Resistance

Table 2

Antimicrobial components of M. domestica microbiome.

Body partsMicrobiome metabolitesInhibited bacteriaReferences

Right wing, body surface, entire body(i) Bacteriophage(i) Pseudomonas spp.(i) Laziz et al. [22]
(ii) Antimicrobial peptide (AMP): mersacidin, subpeptin JM4-B, subtilosin A, sublancin, enterpco E-760, microcin L, microcin J25, colicin, lactocyclicin Q(ii) E. coli(ii) Claresta et al. [20]; Zhao et al. [34]
(iii) MRSA, Streptococcus pyogenes, S. agalactiae, and S. pneumoniae(iii) Simons et al. [35]
(iv) S. aureus, S. faecalis, Salmonella sp., and Shigella flexneri(iv) Yang et al. [36]
(v) Enterococcus faecalis and Listeria monocytogenes
(vi) Yersinia spp., Campylobacter spp. Staphylococcus spp. Listeria monocytogenes
(vii) Pseudomonas aeruginosa
(viii) Lactoccocus spp.

Hemolymph(i) AMP: cecropin, defensins, Hf-1, MDAP-2, a thermal stable antimicrobial proteinS. aureus, S. epidermidis, and P. aeruginosa(i) Liang et al. [37]; Wang et al. [38]; Dang et al. [39]; Hou et al. [10]; Pei et al. [40]; Hao et al. [41]
(ii) Lysozyme(ii) Kawasaki and Andoh [42]

Body extract(i) The butanol fraction obtained from ethanol(i) MRSA and VRE strains(i) Park et al. [25]
(ii) Methanolic whole body extract: 1-lysophosphatidylethanolamine (C16:1) (1-LPE)(ii) B. thuringiensis and Saccharomyces cerevisiae(ii) Meylaers [24]

Cuticular lipidMixtures of alcoholsRhodococcus equi, Candida lipolytica, C. tropicalis(i) Gołêbiowski [14]

Digestive trackAMP: mersacidin, subpeptin JM4-B, subtilosin A, sublancin, microcin L, microcin J25, and colicin(i) MRSA, Streptococcus pyogenes, S. agalactiae, and S. pneumoniae(i) Simons et al. [35]
(ii) S. aureus, S. faecalis, Salmonella sp., and Shigella flexneri(ii) Yang et al. [36]
(iii) Enterococcus faecalis and Listeria monocytogenes
(iv) E. coli, Salmonella enterica, Shigella spp., and Pseudomonas aeruginosa