The Role of Antioxidant Activity of Chitosan-Pinus merkusii Extract Nanoparticle in against Lead Acetate-Induced Toxicity in Rat Pancreas

Figure 3

Normal of pancreas sections in control group (a). Histopathological view of pancreas sections in lead acetate treated group shown degenerative and necrotic changes (black arrow) in the islets of Langerhans as compared to control group (b). Rat treated with Chitosan-Pinus merkusii extract nanoparticles 600 mg/kg showed regeneration (e), while Chitosan-Pinus merkusii extract nanoparticles 300 mg/kg (c), and 150 mg/kg (d) showed degeneration in the islets of Langerhans, using haematoxyline and eosin stain technique (×400).

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