Temporal Bacteriostatic Effect and Growth Factor Loss in Equine Platelet Components and Plasma Cultured with Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus: A Comparative In Vitro Study

Table 4

TGF-₁ (pg/mL) concentration in every blood component cultured with either MSSA or MRSA at 6 hours.

Blood components	MSSA	MRSA
Platelet-rich plasma (PRP)	4038 (3440)^a	4700 (2934)^g
Platelet-rich gel (PRG)	3064 (1184)^b	3608 (1512)
Leukocyte-poor plasma (LPP)	3904 (1596)^c	3088 (1904)^h,i
Leukocyte-poor gel (LPG)	3116 (1469)^c,d	2838 (1626)^c,d
Plasma	2032 (938)^e	1722 (948)^e
Heat-inactivated plasma (IP)	1590 (1085)^e	1460 (903)^e
PRP + NID	6688 (3548)^f	6688 (3548)^f
LPP + NID	4400 (1362)	4400 (1362)

Lowercase letters represent significant differences in the same column. ^aSignificantly different from PRG ( > 0.05), LPG ( > 0.01), plasma ( > 0.001), IP ( > 0.001), and PRP + NID ( > 0.05). ^bSignificantly different from LPG ( > 0.01), plasma ( > 0.001), IP ( > 0.001), PRP + NID ( > 0.001), and LPP + NID ( > 0.001). ^cSignificantly different from plasma ( > 0.001), IP ( > 0.001), and PRP + NID ( > 0.001). ^dSignificantly different from LPP + NID ( > 0.001). ^eSignificantly different from PRP + NID and LPP + NID ( > 0.001). ^fSignificantly different from LPP + NID ( > 0.01). ^gSignificantly different from LPG ( > 0.01), plasma ( > 0.001), IP ( > 0.001), and PRP + NID ( > 0.05). ^hSignificantly different from plasma ( > 0.001), IP ( > 0.001), and PRP + NID ( > 0.01). ⁱSignificantly different from LPP + NID ( > 0.01). Significantly different concentrations for both bacteria in PRG ( > 0.05). NID: nonionic detergent.