Research Article
Bone Metastases in Patients with Leiomyosarcoma: A Retrospective Analysis of Survival and Surgical Management
Table 5
Cox regression analysis of survival in 45 patients with metastatic leiomyosarcoma to the bone.
| Variable | Hazard ratio (95% CI) | P |
| Primary LMS | | | Extremity soft tissue | 2.5 (0.57–11) | 0.23 | Uterine | 0.82 (0.27–2.5) | 0.72 | Lung | 125 (5.3–2998) | 0.003 | H&N | 0.59 (0.05–6.7) | 0.67 | Unknown | 9.4 (1.7–52) | 0.01 | Location of bone metastasis† | | | Appendicular | 0.90 (0.11–7.6) | 0.92 | Axial | 0.64 (0.22–1.8) | 0.41 | Sex‡ | 1.1 (0.26–4.8) | 0.88 | Visceral metastases | 1.5 (0.27–8.1) | 0.65 | Number of metastases|| | 1.3 (0.33–5.5) | 0.69 | Pathologic fracture | 5.4 (1.8–16) | 0.002 | Surgical management | 0.41 (0.16–1.0) | 0.06 |
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Retroperitoneal; †metastases in axial and appendicular locations; ‡female; ||one metastasis. |