Research Article

Adult Pleomorphic Rhabdomyosarcomas: Assessing Outcomes Associated with Radiotherapy and Chemotherapy Use in the National Cancer Database

Table 5

Factors associated with receipt of radiotherapy.

Receipt of radiotherapyUnivariate analysisMultivariate analysis
OR (95% CI) valueOR (95% CI) value

Age
<70 years11
≥70 years0.62 (0.36–1.09)0.0960.55 (0.30–1.00)0.052
Gender
Male11
Female0.50 (0.29–0.87)0.0140.40 (0.22–0.74)0.003
Race
Non-Hispanic White1
Non-Hispanic Black1.45 (0.53–4.00)0.471
Hispanic0.77 (0.27–2.21)0.621
Other4.02 (0.87–18.50)0.074
Facility area
Metropolitan1
Urban1.31 (0.53–3.21)0.556
Rural1.64 (0.31–8.66)0.562
Unknown1.64 (0.31–8.66)0.562
Facility location
East1
South0.61 (0.27–1.38)0.235
Central0.96 (0.40–2.28)0.922
West0.90 (0.37–2.15)0.808
Unknown1.53 (0.49–4.75)0.466
Facility type
Non-academic1
Academic1.14 (0.65–2.01)0.648
Insurance
Commercial1
Medicare0.77 (0.44–1.36)0.369
Medicaid2.39 (0.64–8.98)0.198
Uninsured..
Other1.49 (0.28–8.06)0.642
Distance to treatment facility
≤40 miles1
>40 miles1.23 (0.67–2.23)0.503
Zip code education level
≥21%1
13%–20.9%0.83 (0.35–1.97)0.666
7%–12.9%0.80 (0.35–1.84)0.598
<7%1.58 (0.66–3.82)0.307
Zip code income level
<38,0001
38,000–47,9990.72 (0.30–1.72)0.460
48,000–62,9990.95 (0.42–2.15)0.896
≥63,0001.27 (0.55–2.91)0.572
Charlson/Deyo score
01
10.64 (0.30–1.37)0.256
20.43 (0.09–1.97)0.274
31.71 (0.17–16.74)0.646
Primary site
Extremity11
Head and neck0.54 (0.16–1.80)0.3140.45 (0.13–1.55)0.205
Thorax0.27 (0.11–0.67)0.0050.21 (0.08–0.55)0.001
Abdomen/pelvis0.26 (0.13–0.52)<0.0010.22 (0.10–0.45)<0.001
Other/NOS0.38 (0.02–6.30)0.5030.20 (0.01–3.39)0.266
Tumor size
<5 cm1
5.1–10 cm1.38 (0.69–2.79)0.366
10.1–15 cm1.45 (0.63–3.34)0.385
>15 cm0.72 (0.30–1.74)0.470
Grade
II1
III1.37 (0.40–4.63)0.614
Receipt of chemotherapy
No1
Yes1.32 (0.76–2.27)0.321
Year of diagnosis
2004–20071
2008–20110.61 (0.31–1.20)0.151
2012–20151.09 (0.56–2.11)0.806