Research Article
Adult Pleomorphic Rhabdomyosarcomas: Assessing Outcomes Associated with Radiotherapy and Chemotherapy Use in the National Cancer Database
Table 4
Factors associated with receipt of chemotherapy.
| Receipt of chemotherapy | Univariate analysis | Multivariate analysis | OR (95% CI) | value | OR (95% CI) | value |
| Age | <70 years | 1 | | 1 | | ≥70 years | 0.15 (0.08–0.28) | <0.001 | 0.17 (0.08–0.39) | <0.001 | Gender | Male | 1 | | — | — | Female | 0.76 (0.45–1.28) | 0.301 | — | — | Race | Non-Hispanic White | 1 | | — | — | Non-Hispanic Black | 2.42 (0.92–6.33) | 0.072 | — | — | Hispanic | 0.50 (0.17–1.46) | 0.205 | — | — | Other | 1.30 (0.44–3.85) | 0.635 | — | — | Facility area | Metropolitan | 1 | | — | — | Urban | 1.05 (0.46–2.37) | 0.915 | — | — | Rural | 0.17 (0.02–1.44) | 0.105 | — | — | Unknown | 1.63 (0.35–7.45) | 0.531 | — | — | Facility location | East | 1 | | 1 | | South | 0.70 (0.32–1.52) | 0.367 | 0.88 (0.35–2.18) | 0.775 | Central | 1.05 (0.47–2.34) | 0.907 | 1.03 (0.41–2.59) | 0.944 | West | 1.04 (0.46–2.33) | 0.928 | 1.13 (0.45–2.86) | 0.795 | Unknown | 5.75 (1.84–17.98) | 0.003 | 3.65 (0.95–13.95) | 0.059 | Facility type | Non-academic | 1 | | 1 | | Academic | 1.39 (0.81–2.41) | 0.234 | 1.23 (0.65–2.34) | 0.520 | Insurance | Commercial | 1 | | 1 | | Medicare | 0.29 (0.16–0.51) | <0.001 | 0.91 (0.42–1.96) | 0.801 | Medicaid | 2.49 (0.76–8.10) | 0.130 | 2.72 (0.72–10.24) | 0.140 | Uninsured | 0.38 (0.03–4.34) | 0.438 | 0.43 (0.03–5.48) | 0.517 | Other | 0.26 (0.05–1.32) | 0.103 | 0.33 (0.05–2.03) | 0.233 | Distance to treatment facility | ≤40 miles | 1 | | — | — | >40 miles | . | . | — | — | Zip code education level | ≥21% | 1 | | 1 | | 13%–20.9% | 0.95 (0.41–2.22) | 0.910 | 1.03 (0.37–2.82) | 0.961 | 7%–12.9% | 1.81 (0.82–3.98) | 0.140 | 1.64 (0.65–4.17) | 0.298 | <7% | 2.16 (0.96–4.84) | 0.062 | 2.72 (1.02–7.25) | 0.045 | Zip code income level | <38,000 | 1 | | — | — | 38,000–47,999 | 1.27 (0.54–2.96) | 0.586 | — | — | 48,000–62,999 | 1.73 (0.79–3.82) | 0.174 | — | — | ≥63,000 | 1.98 (0.90–4.36) | 0.089 | — | — | Charlson/Deyo score | 0 | 1 | | — | — | 1 | 0.72 (0.35–1.49) | 0.374 | — | — | 2 | 0.45 (0.09–2.39) | 0.350 | — | — | 3 | . | . | — | — | Primary site | Extremity | 1 | | — | — | Head and neck | 4.27 (1.11–16.38) | 0.034 | — | — | Thorax | 1.55 (0.65–3.73) | 0.325 | — | — | Abdomen/pelvis | 1.00 (0.51–1.95) | 0.995 | — | — | Tumor size | <5 cm | 1 | | — | — | 5.1–10 cm | 1.28 (0.64–2.55) | 0.486 | — | — | 10.1–15 cm | 2.30 (1.04–5.06) | 0.039 | — | — | >15 cm | 1.10 (0.46–2.60) | 0.831 | — | — | Grade | II | 1 | | — | — | III | 0.65 (0.19–2.20) | 0.493 | — | — | Receipt of radiotherapy | No | 1 | | — | — | Yes | 1.35 (0.80–2.26) | 0.257 | — | — | Year of diagnosis | 2004–2007 | 1 | | 1 | | 2008–2011 | 2.12 (1.11–4.04) | 0.023 | 1.75 (0.81–3.77) | 0.152 | 2012–2015 | 0.93 (0.49–1.74) | 0.810 | 0.84 (0.40–1.73) | 0.633 |
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