Clinical Outcomes and Prognostic Factors for Patients with Malignant Peripheral Nerve Sheath Tumour
Table 4
Patient-, tumour-, and treatment-related characteristics and univariate analysis of prognostic factors for postmetastatic survival in 20 patients with metastatic MPNST who underwent surgery of the primary tumour.
Factors
N (%)
5-year postmetastatic survival (%)
value
Age
≤50
6 (30)
50
0.444
>50
14 (70)
17.9
Gender
Male
14 (70)
28.6
0.855
Female
6 (30)
25
NF1 status
Present
12 (60)
27.8
0.666
Absent
8 (40)
25
Location
Extremity
8 (40)
31.2
0.48
Trunk
9 (45)
22.2
Head and neck
3 (15)
33.3
Size
≤5 cm
5 (29.4)
20
0.693
>5 cm
12 (70.6)
31.2
NA
3
—
—
Depth
Superficial
6 (31.6)
0
0.384
Deep
13 (68.4)
38.5
NA
1
—
—
Margin status
Negative
10 (50)
33.3
0.149
Positive
10 (50)
20
Number of metastases
≤3
14 (70)
34.3
0.161
>3
6 (30)
0
Surgery for metastases
Yes
7 (35)
53.6
0.059
No
13 (65)
11.5
Chemotherapy for metastases
Yes
10 (50)
25
0.366
No
10 (50)
30
Surgery and/or chemotherapy for metastases
Yes
13 (65)
42.2
<0.001
No
7 (35)
0
MPNST, malignant peripheral nerve sheath tumour; NF1, neurofibromatosis Type 1; NA, not available.
