Clinical Outcomes and Prognostic Factors for Patients with Malignant Peripheral Nerve Sheath Tumour

Table 1

Patient-, tumour-, and treatment-related characteristics and univariate analysis of prognostic factors for OS in 60 patients with MPNST.

Factors		N (%)	5-year OS (%)	value
Age	≤50	27 (45)	59.6	0.598
	>50	33 (55)	77.6
Gender	Male	31 (51.7)	60.3	0.059
	Female	29 (48.3)	79.7
NF1 status	Present	32 (53.3)	63.4	0.342
	Absent	28 (46.7)	76.8
Location	Extremity	19 (31.7)	89.5	0.164
	Trunk	35 (58.3)	56.8
	Head and neck	6 (10)	83.3
Size	≤5 cm	24 (42.1)	90.3	0.045
	>5 cm	33 (57.9)	57
	NA	3	—	—
Depth	Superficial	20 (33.9)	82.5	0.367
	Deep	39 (66.1)	62.6
	NA	1	—	—
Grade	1	12 (21.1)	100	0.095
	2 or 3	45 (78.9)	62.6
	NA	3	—	—
Stage	Localised	55 (91.7)	74.1	0.006
	Metastatic	5 (8.3)	20
Surgery	Yes	52 (86.7)	78.9	<0.001
	No	8 (13.3)	0

OS, overall survival; MPNST, malignant peripheral nerve sheath tumour; NF1, neurofibromatosis Type 1; NA, not available.