Research Article
Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research
Table 1
List of the established, ready-to-use tissue microarrays.
| Institutions that contributed samples | Name of tissue microarrays | Soft tissue sarcoma subtypes included | Number of cases | Number of blocks | Number of cores per block | Core size (mm) |
| UZ Leuven and collaborating institutions | UZL_PT_TMA_multiple subtype STS | Angiosarcoma | 7 | 7 | 2 | 1.0 | Dedifferentiated liposarcoma | 10 | 10 | Pleomorphic liposarcoma | 10 | 10 | Myxoid liposarcoma | 10 | 10 | Leiomyosarcoma | 9 | 9 | Malignant peripheral nerve sheath tumor | 10 | 10 | Myxofibrosarcoma | 11 | 11 | Rhabdomyosarcoma | 7 | 7 | Synovial sarcoma | 10 | 10 | Undifferentiated pleomorphic sarcoma | 9 | 9 | UZL_PT_TMA_CCSA | Clear cell sarcoma | 22 | 35 | 2 | 1.0 | UZL_PT_TMA_ASPS | Alveolar soft part sarcoma | 12 | 16 | 3 | 1.5 | UZL_PT_TMA_IMFT | Inflammatory myofibroblastic tumor | 12 | 12 | 3 | 1.5 | UZL_PT_TMA_ARMS | Alveolar rhabdomyosarcoma | 21 | 34 | 2 | 1.0 | UZL_PT_TMA_LMS | Leiomyosarcoma | 55 | 131 | 2 | 1.0 | UZL_PT_TMA_GIST | Gastrointestinal stromal tumor | 72 | 76 | 2 | 1.0 | UZL_PT_TMA_LPS | Well-differentiated liposarcoma | 14 | 20 | 3 | 1.0 | Dedifferentiated liposarcoma | 11 | 16 | Pleomorphic liposarcoma | 6 | 7 | Myxoid liposarcoma | 10 | 19 | UZL_PT_TMA_SFT | Solitary fibrous tumor | Under construction | UZL_PT_TMA_ANGS | Angiosarcoma | In preparation | UZL_PT_TMA_SYNSA | Synovial sarcoma | In preparation |
| EORTC phase 2 trial 90101 (CREATE) | CREATE_TMA_CCSA | Clear cell sarcoma | 32 | 32 | 3 | 1.5 | CREATE_TMA_ASPS | Alveolar soft part sarcoma | 47 | 49 | 3 | 1.5 | CREATE_TMA_IMFT | Inflammatory myofibroblastic tumor | 21 | 21 | 3 | 1.5 |
|
|
EORTC: European Organisation for Research and Treatment of Cancer
|