Research Article

Ifosfamide, Carboplatin, and Etoposide (ICE) in Combination with Regional Hyperthermia as Salvage Therapy in Patients with Locally Advanced Nonmetastatic and Metastatic Soft-Tissue Sarcoma

Table 3

Radiographic response to ICE + RHT treatment. For patients receiving tumor resection during or directly after ICE + RHT, radiographic response is given for the latest time point prior to resection. Percentages of CR, PR, NC and PD are given as proportions of patients with measurable disease.

Locally advanced disease (LA-STS, n = 54)Metastatic disease (M-STS, n = 56)

No. (%)No. (%)
No measurable disease10 (18.5)1 (1.8)
Measurable disease44 (81.5)55 (98.2)
CR1 (2.3)0 (0.0)
PR8 (18.2)6 (10.9)
SD17 (38.5)20 (36.4)
PD9 (20.5)24 (43.6)
Could not be evaluated9 (20.5)5 (9.1)
Objective response9 (20.5)6 (10.9)
Disease control26 (59.1)26 (47.3)

CR, complete response; SD, stable disease; PD, progressive disease; PR, partial response.