Patient and Tumour Characteristics of Adult Head and Neck Soft Tissue Sarcomas: A Systematic Review and Meta-Analysis

Table 2

Histological subtypes.

	Mahmoud et al. [7]	Andrä et al. [8]	González-González et al. [9]	Vitzthum et al. [10]	Tejani et al.[6]	Penel et al. [11]	Sidappa and Krishnamurthy [12]	Park et al. [13]	Total
Alveolar soft part sarcoma	—	—	—	—	1	—	—	3	4
Angiosarcoma	—	9	—	14	4	5	—	15	47
Carcinosarcoma	—	—	—	—	1	—	—	—	1
Chondrosarcoma	—	—	—	—	—	—	—	8	8
DFSP^▪	—	—	—	1	—	—		16	17
Epithelioid sarcoma	—	—	—	—	1	1	—	—	2
Ewing’s sarcoma/PNET^◊	—	—	—	—	—	—	—	4	4
Fibrosarcoma/fibromatous sarcoma^○	125	—	—	—	1	2	1	7	136
Histiocytic sarcoma	—	—	—	—	1	—	—	—	1
Leiomyosarcoma	76	—	—	5	3	—	1	4	89
Lipomatous sarcoma^∆	31	—	—	3	4	—	—	10	48
Low-grade fibromyxoid sarcoma	—	—	—	—	—	—	—	2	2
MFH/undiff. pleo./UPS^∞	—	5	—	9	—	2	6	3	25
Neurofibromatous sarcoma^□	46	—	9	1	—	—	5	—	61
Osteosarcoma	—	—	—	—	—	—	—	5	5
Others^•	—	8	—	3	—	—	—	5	16
Peripheral neuroectodermic tumour	—	—	—	—	—	3	—	—	3
Rhabdomyosarcoma	—	—	7	1	5	7	—	24	44
Spindle cell	—	—	—	4	3	—	10	9	26
Synovial sarcoma	34	4	—	6	6	2	1	7	60
Uncommon sarcoma subtypes^†	139	—	—	—	—	—	2	—	141
Undifferentiated sarcoma	—	—	—	—	—	3	—	—	3
Unidentified sarcoma^♦	215	—	—	—	—	—	—	—	215
Vascular sarcoma^‡	122	—	—	2	—	—	1	—	125

Not all of the histological subtypes were reported. ^▪Dermatofibrosarcoma protuberans. ^◊Primitive neuroectodermal tumour. ^○Including fibrosarcoma NOS, fibromyxoma, and fibrous histiocytoma. ^∆Including myxosarcoma, angiomyxoma, atypical lipoma, liposarcoma NOS, fibromyxolipoma, myxoid, round cell, pleomorphic, mixed, and dedifferentiated liposarcoma, and spindle cell lipoma. ^∞MFH = malignant fibrous histiocytoma, undiff. pleo. = undifferentiated pleomorphic sarcoma. UPS = unclassified pleomorphic sarcoma. ^□Including neurosarcoma and malignant peripheral nerve sheath tumour. ^•Andrä et al. [8], not otherwise specified; Vitzthum et al. [10], dendritic cell sarcoma, chordoma, and hemangioengothelioma; Park et al. [13], folicular dendritic cell sarcoma and teratocarcinosarcoma. ^†Including clear cell, dermatofibrosarcoma, rhabdomyosarcoma, epithelioid, desmoplastic small round cell tumour, fascial, infantile, angiomatoid, fibrous histiocytoma, rhabdoid, giant cell tumour of soft part, and alveolar soft part. ^♦Sarcomatosis not otherwise specified (NOS), spindle cell, giant cell, small cell, and undifferentiated sarcoma. ^‡Including hemangiosarcoma, malignant hemangioendothelioma, epithelioid hemangioendothelioma, malignant hemangiopericytoma, hemangiopericytoma, and lymphangiosarcoma.