Research Article

Revisiting the Role of Radiation Therapy in Chondrosarcoma: A National Cancer Database Study

Table 1

Patient characteristics.

N (%)No radiation (n = 4742)Radiation (n = 680)High dose >60 Gy (n = 228)Low dose 40–60 Gy (n = 204)Palliative <40 Gy (n = 107)Conventional (n = 294)Advanced (n = 245)

Age, mean (SD) in years52 (52-53)55 (53–56)52 (50–54)58 (55–60)60 (56–63)58 (56–60)50 (48–53)

GenderFemale2272 (48)308 (45)102 (45)91 (45)52 (49)139 (47)110 (45)

RaceAsian116 (3)18 (3)4 (2)6 (3)3 (3)6 (2)8 (3)
Black319 (7)49 (7)10 (4)15 (7)12 (11)21 (7)14 (6)
White4129 (89)595 (89)209 (92)179 (89)89 (85)262 (90)215 (90)

Hispanic ethnicity343 (8)67 (10)27 (12)17 (9)10 (10)27 (10)26 (11)

Comorbidity03964 (84)559 (82)183 (80)165 (81)91 (85)235 (80)212 (87)
1616 (13)92 (14)37 (16)28 (14)12 (11)48 (16)24 (10)
>1167 (4)29 (4)8 (4)11 (5)4 (4)11 (4)9 (4)

InsurancePrivate2777 (61)361 (54)122 (54)107 (53)47 (44)140 (48)150 (62)
Government1564 (34)276 (41)87 (39)85 (42)55 (51)130 (45)84 (35)
None220 (5)35 (5)17 (8)9 (4)5 (5)21 (7)9 (4)

Income above median2791 (60)416 (62)142 (62)119 (59)64 (60)173 (59)157 (64)

Academic facility type2375 (66)281 (54)100 (60)74 (44)50 (56)114 (47)107 (64)

For each value, the (%) reflects only the proportion of patients with known values for each variable (unknown values not included in %). Statistical comparisons included RT vs. none, palliative vs. low vs. high doses (non-SRS modalities), and conventional vs. advanced modalities. Fisher’s exact or Pearson chi-square tests were performed for categorical variables. Two-tailed t-test or ANOVA performed for numerical variables (age). Statistical significance indicated by for , for , and for .