Research Article

Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension-Based Chemotherapy in Sarcoma: A Multicenter, Retrospective Study

Table 2

Patient details with chemotherapy regimens and efficacy evaluation.

No.AgeSexIf others, please specifyCancer stageSetting in which NDLS was usedNDLS chemotherapy usedOverall response as per the RECIST (1.1)

148MaleHigh-grade pleomorphic sarcoma of mandibleIIINeoadjuvant settingNDLS plus gemcitabineCR
242MaleLeiomyosarcomaIIAdjuvant settingNDLS plus gemcitabineNot applicable
335MaleLeiomyosarcomaIIAdjuvant settingNDLS plus gemcitabineNot applicable
455FemaleLeiomyosarcomaIIAdjuvant settingNDLS plus gemcitabineNot applicable
549FemaleLeiomyosarcomaIVMetastatic settingNDLS plus gemcitabineNE
644FemaleLeiomyosarcomaIVMetastatic settingNDLS plus gemcitabineSD
746FemaleLeiomyosarcomaIVMetastatic settingNDLS plus gemcitabineCR
858FemaleLeiomyosarcomaIVMetastatic settingNDLS plus gemcitabinePR
959MaleMalignant fibrous histiocytoma of right thighIVMetastatic settingNDLS plus gemcitabinePR
1052FemaleExtraskeletal myxoid chondrosarcomaIVMetastatic settingNDLS plus cyclophosphamidePD
1119FemaleOsteosarcoma of left femurIVMetastatic settingNDLS plus gemcitabinePD

Note. Efficacy response was not evaluated for patients in adjuvant setting. Abbreviations: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; NDLS, nanosomal docetaxel lipid suspension; NE, not evaluated.