The Fusion Oncogene FUS-CHOP Drives Sarcomagenesis of High-Grade Spindle Cell Sarcomas in Mice

Figure 6

Determination of endogenous chromosomal rearrangement efficiency in vitro and in vivo. (a) Schematic of in vitro and in vivo translocation generation via adenovirus. (b) In vitro and in vivo PCR validation of AdFC-generated t(7;10). (c) ddPCR quantification of translocation events in vitro. (d) ddPCR quantification of translocation efficiency in vitro.