Periosteal Osteosarcoma: A Single-Institutional Study of Factors Related to Oncologic Outcomes

Table 2

Summary of the contemporary literature regarding periosteal osteosarcoma.

Study	N	Gender ratio (M : F)	Average age of presentation (range) (years)	Mean follow-up (range) (years)	10-year overall survival (%)	Chemotherapy used (%)	Medullary involvement (%)	Local recurrence (%)	Metastasis rate (%)
Bertoni et al. [3]	20	9 : 11	Mean 19.6 (11–53)	7.9 (0.4–39)	85	10	—	40	15
Hall et al. [16]	6	3 : 3	Mean 25.3 (15–40)	2.9 (1.1–5)	—	50	50	0	16.7
Ritts et al. [5]	22	8 :  14	Mean 20.5 (9–47)	10.0 (1.4–29.3)	71.3	9.1	0	13.6	13.6
Revell et al. [14]	17	10 : 7	Median 18 (10–35)	6.8 (0.8–16.7)	88	82	23.5	5.9	0
Grimer et al. [12]	119	54 : 64	Median 18 (8–72)	7.1 (0.5–21)	83	68	—	6.7	14.2
Rose et al. [2]	29	13 : 16	Mean 20.6 (9–47)	15.8 (4–51)	83	31	0	17.2	17.2
Cesari et al. [11]	33	19 : 14	Median 16 (6–32)	Median 10.1 (0.75–30.5)	84	42	65.2^†	21.2	12.1
Gulia et al. [15]	18	12 : 6	Mean 16.3 (5–26)	Median 5.1 (1.5–10.8)	83.3 (5 y OS)	89	44.4	11	22.2
This study	18	6 : 12	Mean 20.8 (10–56)	10.4 (1–27.1)	77.1	61	50	5.6	11.1

Surviving cohort; ^†23 of 33 subjects assessed had medullary involvement.