Ovary-Sparing Radiation Planning Techniques Can Achieve Ovarian Dose Reduction for Soft Tissue Sarcoma of the Buttock and Thigh
Table 3
Dosimetric comparison of mean bilateral ovary dose (MBOD) and mean contralateral ovary dose (MCOD) for standard plans and ovary-sparing plans by anatomic location ().
Tumor distance from pubic symphysis
Standard plan
Ovary-sparing plan
value
Tumor < 8 cm from pubic symphysis, MBOD (cGy) (SD)
10
619 (765)
376 (540)
0.018
Tumor 8 cm from pubic symphysis, MBOD (cGy) (SD)
13
678 (1184)
566 (1022)
0.17
Tumor < 8 cm from pubic symphysis, MCOD (cGy) (SD)
10
249 (575)
72 (109)
0.128
Tumor 8 cm from pubic symphysis, MCOD (cGy) (SD)
13
211 (277)
86 (442)
0.222
Tumor subsite, MBOD (cGy)
Proximal medial thigh (SD)
13
445 (721)
293 (494)
0.008
Other thigh, MBOD (SD)
6
95 (217)
19 (309)
0.33
Buttock, MBOD (SD)
4
2161 (1170)
1800 (1116)
0.20
Tumor subsite, MCOD (cGy)
Proximal medial thigh (SD)
13
167 (255)
70 (50)
0.12
Other thigh, MBOD (SD)
6
8.8 (15.6)
7.2 (11.6)
0.36
Buttock, MBOD (SD)
4
781 (881)
210 (104)
0.26
MBOD: mean bilateral ovary dose; SD: standard deviation; cGy: centigray.