Research Article
Reduced Latency in the Metastatic Niche Contributes to the More Aggressive Phenotype of LM8 Compared to Dunn Osteosarcoma Cells
Table 1
Number of regulated (>2-fold; P < 0.05) Dunn/LM8 gene sets enriched in KEGG pathways (DAVID).
| Pathways | Gene count | %1 |
| Pathways in cancer | 31 | 3.78 | Focal adhesion | 22 | 2.68 | Cytokine-cytokine receptor interaction | 19 | 2.31 | Regulation of actin cytoskeleton | 16 | 1.95 | Axon guidance | 14 | 1.71 | Cell adhesion molecules (CAMs) | 14 | 1.71 | Vascular smooth muscle contraction | 11 | 1.34 | ECM-receptor interaction | 10 | 1.22 | Apoptosis | 9 | 1.10 | Basal cell carcinoma | 8 | 0.97 | Complement and coagulation cascades | 8 | 0.97 | Adherens junction | 8 | 0.97 | Hematopoietic cell lineage | 8 | 0.97 | Hedgehog signaling pathway | 7 | 0.85 | Glutathione metabolism | 6 | 0.73 | Prion diseases | 5 | 0.61 | Glycosphingolipid biosynthesis | 4 | 0.49 |
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Proportion of all regulated gene sets.
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