Potential for Modulation of the Fas Apoptotic Pathway by Epidermal Growth Factor in Sarcomas

Table 1

Coexpression matrix for 12 Fas-related genes assayed by RT-PCR in 82 primary sarcomas. Correlation coefficients in bold are significant at 𝑃≤8.0𝐸−05 using the Bonferroni adjustment for multiple comparisons.

	EGF	FADD	DAXX	TGFβ1	CTGF	Fas	SMAD3	SMAD7	CASP8	CASP10	CFLAR	FasL
EGF	1
FADD	−0.03	1
DAXX	0.06	0.57	1
TGFβ1	−0.08	0.27	0.37	1
CTGF	0.11	0.25	0.37	0.62	1
Fas	0.17	0.16	0.44	0.57	0.66	1
SMAD3	0.12	0.20	0.55	0.46	0.41	0.52	1
SMAD7	−0.02	0.12	0.33	0.48	0.50	0.53	0.51	1
CASP8	−0.14	0.31	0.54	0.45	0.30	0.49	0.61	0.54	1
CASP10	0.03	0.35	0.43	0.58	0.48	0.52	0.50	0.49	0.69	1
CFLAR	−0.06	0.31	0.49	0.43	0.36	0.43	0.52	0.53	0.80	0.71	1
FasL	0.04	0.03	−0.03	0.09	0.35	0.23	−0.07	−0.02	0.01	0.17	−0.07	1