Genetic Profiling Differentiates Second Primary Tumors from Metastases in Adult Metachronous Soft Tissue Sarcoma

Table 2

Recurrent high-level amplifications and homozygous deletions.

Chromosome	No of tumors	Cytoband	Start position	Size (Mbp)	HLA/Hz del^*	Cancer related genes
1	2	1p32.1	58571482	1.2	HLA	JUN
1	3	1q44	241558190	1.0	Hz del
3	2	3q23	141082484	0.51	Hz del
3	3	3p12.1–3	78780218	7.0	HLA
4	2	4q12	54016334	1.5	HLA	PDGFRA, KIT, CHIC2
6	3	6p 12.3–21.2	37360640	11.4	HLA
9	6	9p21.3	21647433	2.4	Hz del	CDKN2A, CDKN2B, MTAP
10	2	10q23.31	89538420	1.5	Hz del	PTEN
11	2	11q13.4–5	71730097	5.3	HLA
13	13	13q14.2	47901160	0.65	Hz del	RB1

^*HLA = high level amplification, Hz del = homozygous deletion.