Clinical Study

Effect on Gait Speed, Balance, Motor Symptom Rating, and Quality of Life in Those with Stage I Parkinson’s Disease Utilizing LSVT BIG®

Table 4

Primary outcomes and MCID.

IDGait Speed
Baseline,
delta post,
delta 3 mths
FGA
Baseline,
delta post,
delta 3 mths
Berg
Baseline,
delta post,
delta 3 mths
UPDRS
Baseline,
delta post,
delta 3 mths
Total MCID
Post,
3 mths

1, , , , , , , , ,
2, , , , , , , , ,
3, , , , , , , , ,
4, , , , , , , , ,
5, , , , , , , , ,
6, , , , , , , , ,
7, , , , , , , , ,
8, , , , , , , , ,
9, , , , , , , , ,
Total MCIDPost: 4Post: 3Post: 4Post: 78 participants achieved MCID in at least 1 measure
3 mths: 53 mths: 33 mths: 43 mths: 7

Meeting MCID required improvement in performance from baseline.
For Functional Gait Assessment, 2 of 9 participants’ baseline was so high that improvement at a level of MCID was not possible. In fact, participant 8 was at the maximum score possible (=30) at baseline.
For Berg, 4 of 9 participants’ baseline was so high that improvement at a level of MCID was not possible.
For UPDRS, 1 participant’s baseline was so low that improvement at a level of MCID was not possible.
Participant 8 scored well on functional assessments at baseline on the FGA, Berg, andUPDRS, so improvement at a level of MCID was not possible to achieve.