Oxidative Medicine and Cellular Longevity

Neurodegeneration, Neurogenesis, and Oxidative Stress


Publishing date
13 Sep 2013
Status
Published
Submission deadline
24 May 2013

Lead Editor

1Development of the Nervous System Laboratory, Ecole Normale Supérieure, IBENS, 46 rue d'Ulm, 75230 Paris Cedex 05, France

2Heidelberg University Biochemistry Center (BZH), Im Neuenheimer Feld 328, 69120 Heidelberg, Germany

3Mitochondria, Bioenergetics, Metabolism and Signaling Laboratory, Cochin Institute, 24 Rue du Faubourg Saint-Jacques, 75014 Paris, France

4Protein Biochemistry, Folding and Stability Laboratory, Instituto Tecnologia Quimica e Biologica (ITQB), UNL, Avenida da República E.A.N., 2784-505 Oeiras, Portugal


Neurodegeneration, Neurogenesis, and Oxidative Stress

Description

Oxidative stress is implicated in the pathophysiology of a wide variety of neurodegenerative disorders, including Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, amyotrophic lateral sclerosis, and stroke. Neural stem cells persist in the adult brain and continue to produce neurons throughout life. However, neurogenesis is impaired in inflammation-associated diseases by mechanisms poorly understood. In addition, the contribution of neurogenesis impairment to disease progression is not clear. Over the last years, stem cell technologies have made this system become an increasingly attractive target for the development of neurodegenerative disease therapies. Thus, further investigation in this subject will clarify several aspects of the implication of oxidative stress and inflammation in neurodegeneration and neurogenesis and contribute to the development of future therapies for neurodegenerative diseases.

We invite authors to submit original research and review articles that seek to refine the understanding of the role of oxidative and nitrosative stress, calcium, mitochondrial functions, and inflammation in the pathophysiology of neurodegenerative diseases and neurogenesis. Potential topics include, but are not limited to:

  • Research in the function of mitochondria, reactive oxygen species, and nitric oxide in neurogenesis and neuron survival
  • Advances in the role of oxidative stress in neurodegeneration
  • Role of inflammation in neurodegeneration and neurogenesis
  • Role of microglia in the neurogenic zones of the brain
  • Research on neuronal and glial proteins involved in neurodegeneration or neurogenesis
  • Recent developments in stem cell therapies for neurodegenerative diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/nnos/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 730581
  • - Editorial

Neurodegeneration, Neurogenesis, and Oxidative Stress

Renata Santos | Carmen Ruiz de Almodóvar | ... | Cláudio M. Gomes
  • Special Issue
  • - Volume 2013
  • - Article ID 725635
  • - Research Article

Friedreich's Ataxia, Frataxin, PIP5K1B: Echo of a Distant Fracas

Aurélien Bayot | Pierre Rustin
  • Special Issue
  • - Volume 2013
  • - Article ID 104024
  • - Review Article

Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets

Rafael Lugo-Huitrón | Perla Ugalde Muñiz | ... | Verónica Pérez-de la Cruz
  • Special Issue
  • - Volume 2013
  • - Article ID 898034
  • - Review Article

Cadmium and Its Neurotoxic Effects

Bo Wang | Yanli Du
  • Special Issue
  • - Volume 2013
  • - Article ID 836760
  • - Review Article

SOD1 and DJ-1 Converge at Nrf2 Pathway: A Clue for Antioxidant Therapeutic Potential in Neurodegeneration

Pamela Milani | Giulia Ambrosi | ... | Cristina Cereda
  • Special Issue
  • - Volume 2013
  • - Article ID 415078
  • - Review Article

Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases

Andrea Tarozzi | Cristina Angeloni | ... | Patrizia Hrelia
  • Special Issue
  • - Volume 2013
  • - Article ID 316523
  • - Review Article

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

Yan Zhao | Baolu Zhao
  • Special Issue
  • - Volume 2013
  • - Article ID 487534
  • - Review Article

Neurodegeneration in Friedreich’s Ataxia: From Defective Frataxin to Oxidative Stress

Cláudio M. Gomes | Renata Santos
  • Special Issue
  • - Volume 2013
  • - Article ID 162152
  • - Review Article

Deconstructing Mitochondrial Dysfunction in Alzheimer Disease

Vega García-Escudero | Patricia Martín-Maestro | ... | Jesús Avila
  • Special Issue
  • - Volume 2013
  • - Article ID 743938
  • - Research Article

Neuroprotective Effect of Tea Polyphenols on Oxyhemoglobin Induced Subarachnoid Hemorrhage in Mice

Haizhen Mo | Ying Chen | ... | Wenke Zhou
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate44%
Submission to final decision78 days
Acceptance to publication48 days
CiteScore4.520
Impact Factor4.868
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