Research Article
Inhibition of Mitochondrial ROS by MitoQ Alleviates White Matter Injury and Improves Outcomes after Intracerebral Haemorrhage in Mice
Figure 4
MitoQ decreased the loss of oligodendrocyte precursor cells (OPCs) and oligodendrocytes 3 days after ICH. (a) Images showing NG-2 or APC immunostaining (green) with DAPI (blue) in the internal capsule of the mice after ICH. (b) The results of the quantitative analysis of the number of APC-positive and NG-2 positive cells in bin areas of the internal capsule; sections, 3 mice per group. (c) The mitochondrial ROS around hematoma were detected by MitoSOX Red 3 days after ICH. (d) The intensity of MitoSOX Red was analyzed show in histogram; mice. The values represent the . Scale bar: (a) 50 μm, (c) 20 μm. ; ; . The black box in panel (a) shows the region of interest in the brain.
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