Comparative Study on Pulmonary Toxicity in Mice Induced by Exposure to Unflavoured and Apple- and Strawberry-Flavoured Tobacco Waterpipe Smoke

Figure 2

Representative light microscopy sections of lung tissues of mice, at the end of a one-month exposure period to either air (control) or plain (P-) waterpipe smoke (WPS) or apple-flavoured (AF-) WPS or strawberry-flavoured (SF-) WPS. (a, b) The air-exposed group shows normal lung tissue with uniform alveolar spaces (thin arrow). (c) The P-WPS group displays a focal area of dilated alveolar spaces (thin arrow). (d) The P-WPS group shows widening of interalveolar spaces with mixed inflammatory cells consisting of macrophages (arrowhead) and neutrophil polymorphs (thin arrow). (e) AF-WPS displays a focal area of dilated alveolar spaces (thin arrow). (f) AF-WPS shows widening of interalveolar spaces with mixed inflammatory cells consisting of macrophages (arrowhead) and neutrophil polymorphs (thin arrow). (g) SF-WPS exhibits focal area of dilated alveolar spaces (thin arrow). (h) SF-WPS shows widening of interalveolar spaces with mixed inflammatory cells consisting of macrophages (arrowhead) and neutrophil polymorphs (thin arrow).

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)