Research Article
Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats
Figure 4
Eze inhibited microglia/macrophage activation and neutrophil infiltration at 24 h after MCAO. (a, c) Immunofluorescence revealed that treatment with Eze reduced the number of MPO-positive cells and Iba-1-positive cells in the ischemic penumbra region. (b, d) Representative western blot bands and quantitative analyses of MPO and Iba-1 protein levels at 24 h after MCAO. vs. sham; # vs. vehicle. per group. Eze: Ezetimibe. μm.
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