Danhong Injection Alleviates Cardiac Fibrosis via Preventing the Hypermethylation of Rasal1 and Rassf1 in TAC Mice

<div>DHI treatment downregulates DNMT3B expression in CF hearts. (a) Quantification of DNMT1 protein level in CF hearts. (b) Quantification of TET3 protein level in CF hearts. (c) Quantification of DNMT3A protein level in CF hearts. (d) Quantification of DNMT3B protein level in CF hearts. (e) Representative Western blots of DNMT1, TET3, DNMT3A, DNMT3B, and GAPDH. (f) Relative mRNA level of Dnmt1 in CF hearts. (g) Relative mRNA level of Tet3 in CF hearts. (h) Relative mRNA level of Dnmt3a in CF hearts. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Danhong Injection Alleviates Cardiac Fibrosis via Preventing the Hypermethylation of Rasal1 and Rassf1 in TAC Mice 