Danhong Injection Alleviates Cardiac Fibrosis via Preventing the Hypermethylation of Rasal1 and Rassf1 in TAC Mice

Figure 2

DHI treatment alleviated TAC-induced CF. (a) Typical H&E staining slides of hearts in various groups under 100x and 400x magnifications. (b) Typical Picrosirius red staining slides of hearts in various groups under 100x and 400x magnifications. (c) Typical Masson’s trichrome staining slides of hearts in various groups under 100x and 400x magnifications. Blue represents the myocardial fibrotic area. Red represents the normal myocardium tissue. (d) The rate of the fibrotic area was measured on Masson’s trichrome-stained slides and compared among groups on 28 days after TAC surgery (). (e) Expression of Twist1 mRNA in hearts was compared among groups (). (f) Expression of Snail mRNA in hearts was compared among groups (). (g) Expression of Slug mRNA in hearts was compared among groups (). . .

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