High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells

Table 2

Percentage of read numbers representing nuclear and mitochondrial transcripts. Shown are total read numbers for all individual biological replicates, i.e., RNAs isolated from human primary endothelial cells cultured in standard medium (con_1-4) or medium containing 1 mg/ml LDL (high_LDL-1-4) and the percentage of reads, which could be mapped to the nuclear or mitochondrial reference genome.

Sample	Nuclear (%)	Mitochondrial (%)	Total # of reads
con_1	96.0	4.0	325,725,044
con_2	95.8	4.2	319,428,178
con_3	93.9	6.1	335,842,395
con_4	96.3	3.7	325,882,327
high_LDL_1	88.9	11.0	328,183,964
high_LDL_2	88.1	11.9	327,355,990
high_LDL_3	89.0	11.0	331,832,849
high_LDL_4	89.0	11.0	331,650,314