Pioglitazone Protects Compression-Mediated Apoptosis in Nucleus Pulposus Mesenchymal Stem Cells by Suppressing Oxidative Stress

<div>Effects of pioglitazone on NP-MSCs apoptosis. (a) Flow cytometric analysis was used to detect cell apoptosis by annexin V/PI staining. (b) Quantitative analysis of the apoptotic NP-MSCs rate. (c) The TUNEL staining was used to investigate apoptotic changes under a fluorescence microscope (100x). (d) Quantitative analysis of TUNEL-positive cells. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Pioglitazone Protects Compression-Mediated Apoptosis in Nucleus Pulposus Mesenchymal Stem Cells by Suppressing Oxidative Stress 