Glycine Suppresses AGE/RAGE Signaling Pathway and Subsequent Oxidative Stress by Restoring Glo1 Function in the Aorta of Diabetic Rats and in HUVECs

Figure 2

Oxidative markers in the serum and aorta homogenates. Total GSH levels (a), SOD levels (b), and MDA levels (c) in serum samples from different groups were measured after 12 weeks of treatment (). Total GSH levels (d), SOD levels (e), and MDA levels (f) in aorta homogenates from different groups were measured after 12 weeks of treatment (). (g) and (h) show the immunohistological analysis of 3-nitrotyrosine in the aorta, magnification 200x. The scale bar indicates 40 μm. IOD: integrated optical density. . , , compared with the control group. , compared with the DM group.

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