Research Article

Prediabetes Induced by Fructose-Enriched Diet Influences Cardiac Lipidome and Proteome and Leads to Deterioration of Cardiac Function prior to the Development of Excessive Oxidative Stress and Cell Damage

Table 5

Alteration of selected cardiac proteins in fructose-fed rats by proteomic analysis. Values are expressed as fold change and value.

Protein namesGene namesFold change value

Alpha B crystallinCryab5.560.047
3-ketoacyl-CoA thiolase (mitochondrial)Acaa24.560.005
Alpha-aminoadipic semialdehyde dehydrogenaseAldh7a14.34≤0.001
60 kDa heat shock protein (mitochondrial)Hspd13.370.010
Myosin 6MYH63.060.003
Peroxiredoxin-6Prdx62.870.001
Superoxide dismutase [Mn] (mitochondrial)Sod2-1.820.033
Protein disulfide-isomeraseP4hb-3.400.001