Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model

Table 3

Effect of treatment with simvastatin on lipid peroxidation, SOD, and Gpx activities in mouse livers with NASH induced by a MCD diet.

	CO+V	SIM 4	NASH+V	NASH+SIM 4
TBARS (nmoles/mg prot)				^$
SOD (U/SOD mg prot)
GPx (nmoles/mg prot)			^#

CO+V: control plus vehicle (); SIM 4: control plus simvastatin 4 mg/kg (); NASH+V: NASH plus vehicle (); NASH+SIM 4: NASH plus simvastatin 4 mg/kg (). versus CO+V, SIM 4, and NASH+V. ^$ against versus CO+V, SIM 4, and CO+V. ^# versus CO+V, SIM 4, and NASH+V.