Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model

<div>Effect of a MCD diet and treatment with simvastatin on NQO1, Keap1, and Nrf2 protein by Western blot analysis. 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CO+V: control plus vehicle; SIM 4: control plus simvastatin 4 mg/kg; NASH+V: NASH plus vehicle; NASH+SIM 4: NASH plus simvastatin 4 mg/kg.</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model 