Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats

Table 2

Oral treatment with Q7 causes oxidative stress in rats. The SOD-like activity represents the autoxidation rate of pyrogallol in an experimental sample and control sample. When the activity is ≥100%, pyrogallol autoxidation is completely inhibited, while the negative value means that it is accelerated by adding Q7.

	Control	Q7	Q7 + Asc	Asc
TBARS (nM)	26 ± 1	33 ± 2	30 ± 3	25 ± 1
SOD-like activity (%)	159 ± 49	−193 ± 100	−36 ± 10	150 ± 39

Values are mean ± standard error of the mean of 5 experiments. Statistically significant differences: versus control.