Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats

Figure 4

Effects of quinone and ascorbate on intracellular Ca²⁺ levels in rat cardiomyocytes. Quinone Q7 (10⁻⁵ M) increased intracellular calcium levels in rat cardiomyocytes (a), but ascorbate (Asc) (2 mM) did not prevent the increase of Q7-induced intracellular calcium (c). Effect of ascorbate on intracellular calcium levels in rat cardiomyocytes (b). Three independent experiments were performed.

(a)

(b)

(c)