Sepiapterin Improves Vascular Reactivity and Insulin-Stimulated Glucose in Wistar Rats

<div>(a, b, and c) Aorta vasodilation. At the end of the study, aorta rings (2 mm) were hung in an upright water muscle bath and analyzed for vasodilation using a dose response to ACh (a) and NO donor S-nitroso-N-acetyl-DL-penicillamine (SNAP, b) and cGMP (c) in intact and denuded endothelium. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Sepiapterin Improves Vascular Reactivity and Insulin-Stimulated Glucose in Wistar Rats 