Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway

<div>A Nrf2 inhibitor, ML385, counteracted the protective effect of ISL on mice with MAP. (a) Representative HE staining of pancreas. (b) Histological scores of pancreas. 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V represents vehicle; S represents saline; H represents high-dose ISL (200 mg/kg); M represents Nrf2 inhibitor, ML385.</div>

Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway 