Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway

Figure 1

Dynamic changes of oxidative stress in the pancreatic tissues of mice induced by caerulein. (a) Representative HE staining of pancreas. (b) Histological scores of pancreas. (c-d) Serum levels of amylase and lipase. (e–g) Protein levels of nuclear Nrf2 and HO-1 in the pancreatic tissues were analyzed by Western blotting. Lamin B1 and β-actin were used as a control for protein loading. (h) Levels of oxidative stress products (SOD, MDA, and GSH) of pancreas. each group.

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