Protective Effects of Miswak (Salvadora persica) against Experimentally Induced Gastric Ulcers in Rats

Figure 2

Light microscopic images of gastric mucosa. (a) The control group showed normal histologic appearance of all parts of the gastric wall. (b) The EtOH-induced gastric ulcer group revealed severe degeneration, necrosis, and hemorrhage of gastric base, neck, and isthmus with sloughing of gastric pits. (c) The EtOH-induced gastric ulcer and treated with S. persica at a dose of 200 mg/kg b.w. group showed moderated degeneration and hemorrhage in the gastric neck, isthmus, and pits with slight vacuolation in the gastric neck. (d) The EtOH-induced gastric ulcer and treated with S. persica at a dose of 400 mg/kg b.w. group showed normal histologic appearance of all gastric portions with only slight vacuolation. Scale bar = 50 µm.