Lycopene: Hepatoprotective and Antioxidant Effects toward Bisphenol A-Induced Toxicity in Female Wistar Rats

Figure 1

Histopathological sections of female Wistar rats. (a) Control group (b), LYC-treated (10 mg/kg) control, (c) BPA-treated (10 mg/kg) group, and (d) BPA (10 mg/kg) and LYC (10 mg/kg) cotreated group. (a) and (b) show normal hepatocytes arranged in radiating cords around central vein (cv). (c) The BPA-treated liver shows dilated vein, bridging fibrosis of portal areas (black arrow), mild leukocytic infiltration (arrowheads), and minute focal hepatocyte necrosis (white arrows). (d) BPA + LYC-treated liver shows amelioration of hepatic lesions with mildly vacuolization of hepatocytes.

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