The Ability of Different Ketohexoses to Alter Apo-A-I Structure and Function In Vitro and to Induce Hepatosteatosis, Oxidative Stress, and Impaired Plasma Lipid Profile in Hyperlipidemic Zebrafish

<div>Electrophoretic characterization of modified apoA-I by each ketohexose. (a) Electrophoretic patterns of the glycated apoA-I in the lipid-free state on native gel (8–25% native gradient gel electrophoresis. Lane 1: native A-I, Lane 2: H2O-A-I, Lane 3: f-A-I, Lane 4: t-A-I, and Lane 5: p-A-I. (b) Glycation extent of apoA-I by each ketohexose treatment (Lane 1: native A-I, Lane 2: H2O-A-I, Lane 3: f-A-I, Lane 4: t-A-I, and Lane 5: p-A-I).</div>

Oxidative Medicine and Cellular Longevity

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Figure 1

Figure 1: The Ability of Different Ketohexoses to Alter Apo-A-I Structure and Function In Vitro and to Induce Hepatosteatosis, Oxidative Stress, and Impaired Plasma Lipid Profile in Hyperlipidemic Zebrafish 

Figure 1 | The Ability of Different Ketohexoses to Alter Apo-A-I Structure and Function In Vitro and to Induce Hepatosteatosis, Oxidative Stress, and Impaired Plasma Lipid Profile in Hyperlipidemic Zebrafish 