Di-(2-Ethylhexyl) Phthalate Increases Obesity-Induced Damage to the Male Reproductive System in Mice
Table 3
MDA, T-AOC, SOD, GSH, H2O2, CAT, and GSH-PX levels of testis tissue of the 6 experimental groups in 12 weeks (±SD).
Group
n
MDA (nmol/mg prot)
T-AOC (U/mg prot)
SOD (U/mg prot)
GSH (mgGSH/g prot)
H2O2 (mmol/g prot)
CAT (U/mg prot)
GSH-PX (U/mg prot)
Control
10
3.3 ± 0.5
0.5 ± 0.2
196.7 ± 37.7
114.8 ± 15.6
3.1 ± 0.58
16.0 ± 0.9
55.7 ± 6.8
DEHP
10
4.3 ± 0.5b
0.5 ± 0.2
90.5 ± 28.4b
99.5 ± 13.5a
2.8 ± 0.61
14.1 ± 1.0b
49.8 ± 10.9
DIO
10
4.2 ± 0.8b
0.5 ± 0.1
135.6 ± 19.4b
91.8 ± 16.3b
7.6 ± 1.7b
14.4 ± 1.8b
40.4 ± 7.1b
DIO + DEHP low
10
5.0 ± 0.7bce
0.4 ± 0.1c
106.2 ± 25.6be
73.7 ± 17.6bdf
8.2 ± 1.5bd
14.3 ± 1.1b
39.3 ± 5.6bc
DIO + DEHP middle
10
5.1 ± 0.7bcf
0.4 ± 0.1ade
89.6 ± 35.2bf
47.6 ± 11.1bdfh
9.7 ± 2.36bdfg
13.2 ± 0.9beh
29.5 ± 3.1bdeg
DIO + DEHP high
10
5.4 ± 0.7bdf
0.3 ± 0.1bdfg
68.4 ± 10.9bfh
38.2 ± 11.8bdfh
11.4 ± 2.2bdfhi
11.4 ± 1.0bdfh
26.3 ± 6.2bdfh
Data are mean ± SD. and denote statistical significance compared with the control group; and denote statistical significance compared with the DEHP group; and denote statistical significance compared with the DIO group; and denote statistical significance compared with the DIO + DEHP low group; denotes statistical significance compared with the DIO + DEHP middle group.