Research Article

Di-(2-Ethylhexyl) Phthalate Increases Obesity-Induced Damage to the Male Reproductive System in Mice

Table 3

MDA, T-AOC, SOD, GSH, H2O2, CAT, and GSH-PX levels of testis tissue of the 6 experimental groups in 12 weeks (±SD).

GroupnMDA
(nmol/mg prot)
T-AOC
(U/mg prot)
SOD
(U/mg prot)
GSH
(mgGSH/g prot)
H2O2
(mmol/g prot)
CAT
(U/mg prot)
GSH-PX
(U/mg prot)

Control103.3 ± 0.50.5 ± 0.2196.7 ± 37.7114.8 ± 15.63.1 ± 0.5816.0 ± 0.955.7 ± 6.8
DEHP104.3 ± 0.5b0.5 ± 0.290.5 ± 28.4b99.5 ± 13.5a2.8 ± 0.6114.1 ± 1.0b49.8 ± 10.9
DIO104.2 ± 0.8b0.5 ± 0.1135.6 ± 19.4b91.8 ± 16.3b7.6 ± 1.7b14.4 ± 1.8b40.4 ± 7.1b
DIO + DEHP low105.0 ± 0.7bce0.4 ± 0.1c106.2 ± 25.6be73.7 ± 17.6bdf8.2 ± 1.5bd14.3 ± 1.1b39.3 ± 5.6bc
DIO + DEHP middle105.1 ± 0.7bcf0.4 ± 0.1ade89.6 ± 35.2bf47.6 ± 11.1bdfh9.7 ± 2.36bdfg13.2 ± 0.9beh29.5 ± 3.1bdeg
DIO + DEHP high105.4 ± 0.7bdf0.3 ± 0.1bdfg68.4 ± 10.9bfh38.2 ± 11.8bdfh11.4 ± 2.2bdfhi11.4 ± 1.0bdfh26.3 ± 6.2bdfh

Data are mean ± SD. and denote statistical significance compared with the control group; and denote statistical significance compared with the DEHP group; and denote statistical significance compared with the DIO group; and denote statistical significance compared with the DIO + DEHP low group; denotes statistical significance compared with the DIO + DEHP middle group.