Research Article

Di-(2-Ethylhexyl) Phthalate Increases Obesity-Induced Damage to the Male Reproductive System in Mice

Table 2

Testosterone, estradiol, and leptin level in the 6 experimental groups ( ± SE).

GroupnTestosterone (ng/ml)Estradiol (ng/ml)Leptin (ng/ml)

Control104.38 ± 0.1529.69 ± 2.381.71 ± 0.11
DEHP102.99 ± 0.23b80.36 ± 9.69b4.01 ± 0.72a
DIO103.02 ± 0.21b47.14 ± 7.01d4.07 ± 0.81a
DIO + DEHP low102.35 ± 0.42b90.42 ± 6.35bf6.01 ± 0.76b
DIO + DEHP middle102.36 ± 0.30b94.04 ± 6.91bf9.10 ± 0.95bdfh
DIO + DEHP high102.18 ± 0.23bce86.49 ± 10.00bf10.04 ± 0.68bdfh

Data are mean ± SE. and denote statistical significance compared with control group; and denote statistical significance compared with the DEHP group; and denote statistical significance compared with the DIO group; denotes statistical significance compared with the DIO + DEHP low group.