Protective Effects of Fullerene C₆₀ Nanoparticles and Virgin Olive Oil against Genotoxicity Induced by Cyclophosphamide in Rats

Table 4

Chromosomal aberrations in rat bone marrow cells after treatment with CP, C₆₀, and VOO.

Groups	Aberration cells (number)	Chromosomal aberration					Total aberrations		Average number of aberration (mean ± SEM)
		(number)	(number)	(number)	(number)	Poly (number)	Number	%
Control	2	1	1	—	—		2	1.00	0.40 ± 0.24
CP	95	80	12	8	7	8	115	57.5	23.00 ± 14.28
C60	25	20	10	6	1	4	41	20.5	8.20 ± 3.29
CP + C60	36	30	10	7	3	2	52	26.0	10.40 ± 5.10
CP + VOO	45	36	7	3	5	5	56	28.0	11.20 ± 6.23

 = ring chromosome,  = deletion in chromatid,  = dicentric chromosome,  = fragmentation chromosomes, and Poly = polyploidy chromosomes. Values are mean of replicates ± SEM. Significant at .