Expression of the NRF2 Target Gene NQO1 Is Enhanced in Mononuclear Cells in Human Chronic Kidney Disease

Figure 1

NQO1 gene expression. (a) Amplification curves and melting curves for NQO1 in monocytes from a patient with CKD 4 (CKD, orange), a hemodialysis patient (CKD 5D, black), and a healthy subject (red). (b) Box and whisker plots (whiskers, minimum to maximum) showing summary data of the NQO1 gene expression in healthy subjects (), CKD 1–5 patients (), and CKD 5D patients () normalized to ACTB, RPL41, and TBP. Comparison by Dunn’s posttest. ; ; .

(a)

(b)