Paradoxical Effect of Nonalcoholic Red Wine Polyphenol Extract, Provinols™, in the Regulation of Cyclooxygenases in Vessels from Zucker Fatty Rats (fa/fa)

Figure 1

Provinols did not affect contractile response to Phe in aortas and SMA from obese ZF rats. Shown are concentration-response curves to phenylephrine (Phe) cumulative concentrations (M) of small mesenteric arteries (SMA, (a)) and rat aortic rings (b) from lean and ZF rats treated or not with Provinols. Values are expressed as mean ± SEM of millinewtons (mN) per mm of vessel length. in each group.

(a)

(b)