Research Article

Spermidine Oxidation-Mediated Degeneration of Retinal Pigment Epithelium in Rats

Figure 2

Spermidine-induced hyperpermeability of the blood-retinal barrier (BRB) in rats. BRB permeability was assessed by vitreous fluorophotometry on days 1, 3, 7, 14, and 28 after the intravitreal administration of spermidine. Each value represents the mean ± standard error of the mean of six to eight eyes. , versus control.