Neuroprotective and Cognitive-Enhancing Effects of Microencapsulation of Mulberry Fruit Extract in Animal Model of Menopausal Women with Metabolic Syndrome

Table 1

The bioactive compounds and biological activities of microencapsulated mulberry fruit extract (MME).

Parameters	Mulberry fruit extract	Microencapsulated mulberry fruit extract	Standard reference
Total phenolic compounds (mg GAE/mg extract)	80.00 ± 0.98	103.89 ± 13.08	—
Flavonoids content (μg quercetin/mg extract)	8.89 ± 0.13	26.56 ± 1.26	—
DPPH (EC50, mg/ml)	2.56 ± 0.08	2.07 ± 0.79	0.03 ± 0.01, ascorbic acid
FRAP (EC50, mg/ml)	280.04 ± 3.14	192.79 ± 15.94	21.04 ± 1.24, ascorbic acid
ABTS (EC50, mg/ml)	4.08 ± 0.02	1.66 ± 0.08	0.20 ± 0.002, Trolox
AChEI (EC50, mg/ml)	0.07 ± 0.002	0.05 ± 0.003	0.02 ± 0.001, donepezil

Data are presented as mean ± SEM. value <0.05 and value < 0.01, compared between MME and mulberry fruit extract.