Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis

Figure 1

Spermidine reduces oxidative stress levels in the EAAC1 KO mouse retina. (a) Representative images of 4-HNE in the retina at 8 weeks old. Scale bar: 100 μm. (b) Quantitative analyses of (a). Data are normalized to the 4-HNE intensity at the GCL in control WT mice (100%). in each group. (c) Representative images of immunoblot analyses of 4-HNE in the retina at 8 weeks old. (d) Quantitative analyses of (c). Data are normalized to the 4-HNE intensity in control WT mice (1.0). in each group. ; . Reproduced from Noro et al. [20].

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