Ginkgo Biloba Ameliorates Subfertility Induced by Testicular Ischemia/Reperfusion Injury in Adult Wistar Rats: A Possible New Mitochondrial Mechanism

Figure 5

Photomicrographs of a cross section of ischemia only group adult rat tests (H&E) showing (a) mild congestion of the connective tissue capsule (CT) with dilated congested blood vessels (BV) with some shrunken seminiferous tubules () and wide peritubular space () and others with thin germinal epithelium and wide lumina (L) (×100). (b) Festoon appearance of tubules with detached basement membrane (), shrunken tubules (upwards black arrow) and wide peritubular space () (×100). (c) Marked loss of general architecture of the seminiferous tubules (SNT) with loss of stratification of germ cells, area of depleted germ cells (D), scanty or hardly detected elongated mature spermatids, degenerated spermatogonia (g), and primary spermatocytes (P) with observed wide large interstitial tissue spaces () and congested blood vessels (BV) (×400). (d) Severely affected tubules with degenerated spermatogonia (g) and primary spermatocytes (P), further lost stages of spermatogenesis, dilated congested blood vessels (BV) together with pyknotic nuclei of some Leydig cells (▲) embedded in acidophilic exudates () (×400). (e) Some seminiferous tubules were filled with acidophilic exudates (T1) while other tubules showed exfoliated cells in their lumina (T2) (×100). (f) One of the tubules showing degenerated germ cells floating in the acidophilic exudates () (×400).

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